BDBM162326 US10307427, Compound 17::US9051313, 17

SMILES CN1CCN(CC1)c1cnc(cc1-n1cnc(c1)C1CC1)C(=O)Nc1csc(n1)-c1nncn1C1CC1

InChI Key InChIKey=LOMLIMUWYBHJOK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162326   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gildead Sciences

US Patent
LigandPNGBDBM162326(US9051313, 17 | US10307427, Compound 17)
Affinity DataIC50: 3.10nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gildead Sciences

US Patent
LigandPNGBDBM162326(US9051313, 17 | US10307427, Compound 17)
Affinity DataIC50: 3.10nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent