BDBM16232 6-phenylpurine compound 20::6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-purine

SMILES Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1ncnc2nc[nH]c12

InChI Key InChIKey=HPWBHQIUIBFTQC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 16232   

LigandPNGBDBM16232(6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-...)
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM16232(6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-...)
Affinity DataIC50: 33nMpH: 7.2 T: 2°CAssay Description:The recombinant alpha catalytic subunit of bovine PKA was assayed with a peptide substrate and test compound in the presence of 40 uM ATP/ [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2007
Entry Details Article
PubMed
LigandPNGBDBM16232(6-{4-[4-(4-chlorophenyl)piperidin-4-yl]phenyl}-9H-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of PKBbeta recombinant by radiometric filter binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed