BDBM162319 US10307427, Compound 10::US9051313, 10

SMILES OC1CCN(C1)c1cnc(cc1-n1cnc(c1)C1CC1)C(=O)Nc1csc(n1)-c1nncn1C1CC1

InChI Key InChIKey=OYQMZDDDXIGQFI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162319   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gildead Sciences

US Patent
LigandPNGBDBM162319(US9051313, 10 | US10307427, Compound 10)
Affinity DataIC50: 3nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Gildead Sciences

US Patent
LigandPNGBDBM162319(US9051313, 10 | US10307427, Compound 10)
Affinity DataIC50: 3nMAssay Description:The assay measures the phosphorylation level of a biotinylated peptide substrate by the ASK1 kinase using HTRF detection (6.1). This is a competitive...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
Go to US Patent