BDBM162277 US9051311, 34

SMILES Fc1cnc(NS(=O)(=O)N2CCc3c(C2)cccc3-c2ccc(cc2C2CCNCC2)C(F)(F)F)s1

InChI Key InChIKey=NZVPKFNBCUVMIZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 162277   

LigandPNGBDBM162277(US9051311, 34)
Affinity DataIC50: 64.5nMAssay Description:In Vitro Assays 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the Ion Works Quat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

LigandPNGBDBM162277(US9051311, 34)
Affinity DataIC50: 1.00E+4nMAssay Description:In Vitro Assays 293 cells stably transfected with either Nav 1.7 or with Nav 1.5 were recorded in population patch-clamp mode with the Ion Works Quat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent

LigandPNGBDBM162277(US9051311, 34)
Affinity DataIC50: 50nMAssay Description:293 cells stably transfected with human Navl .7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/25/2016
Entry Details
Go to US Patent