BDBM162189 US9682995, 88

SMILES COc1ccc(NC(=O)c2c(C)nsc2Nc2nc3ccc(F)cc3s2)cn1

InChI Key InChIKey=BNVWHRWPOGVWJF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162189   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1 [704-1085](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM162189(US9682995, 88)
Affinity DataIC50: 1.70E+4nMpH: 8.0Assay Description:Recombinant fusion proteins of GST and human CDK2 and of GST and human CycE, expressed in insect cells (Sf9) and purified by Glutathion-Sepharose aff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM162189(US9682995, 88)
Affinity DataIC50: 2.00E+4nMpH: 7.5 T: 2°CAssay Description:N-terminally His6-tagged recombinant catalytic domain of human Bub1 (amino acids 704-1085), expressed in insect cells (Hi5) and purified by Ni-NTA af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2018
Entry Details
US Patent