BDBM162019 US9669028, 26 N-(1-(3,4-difluorobenzylpiperidin-3-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridid-5-amine

SMILES Cc1n[nH]c2ncc(NC3CCCN(Cc4ccc(F)c(F)c4)C3)cc12

InChI Key InChIKey=PUTXYOFFEZMJLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 162019   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM162019(US9669028, 26 N-(1-(3,4-difluorobenzylpiperidin-3-...)
Affinity DataIC50: 500nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent

TargetLeucine-rich repeat serine/threonine-protein kinase 2 [G2019S](Human)
Arrien Pharmaceuticals

US Patent
LigandPNGBDBM162019(US9669028, 26 N-(1-(3,4-difluorobenzylpiperidin-3-...)
Affinity DataIC50: 500nMAssay Description:Procedure: Enzyme was incubated with substrate peptide in reaction buffer in the presence and absence of test compounds or Staurosporine. All additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2018
Entry Details
Go to US Patent