BDBM161777 US9682976, 215::US9682976, 218::US9682976, 224

SMILES CC1(C)C[C@@H](C[C@@H]2CCCN12)Nc1nc(Nc2ccc(OCCCO)c(c2)-n2cnnn2)ncc1F

InChI Key InChIKey=PWDDRWHQJQYYAK-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 161777   

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161777(US9682976, 218 | US9682976, 224 | US9682976, 215)
Affinity DataEC50: <100nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161777(US9682976, 218 | US9682976, 224 | US9682976, 215)
Affinity DataEC50: <100nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161777(US9682976, 218 | US9682976, 224 | US9682976, 215)
Affinity DataEC50: <100nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
US Patent