BDBM161384 US9108956, 10::US9108956, 11::US9108956, 8::US9108956, 9

SMILES OC(=O)CC1CCC(OC1)c1ccc(cc1)-c1ccc(Nc2nnc(o2)C2CCC2)cc1

InChI Key InChIKey=HIHFZDGOQGUUEM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161384   

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161384(US9108956, 10 | US9108956, 9 | US9108956, 11 | US9...)
Affinity DataIC50: 760nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161384(US9108956, 10 | US9108956, 9 | US9108956, 11 | US9...)
Affinity DataIC50: 130nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161384(US9108956, 10 | US9108956, 9 | US9108956, 11 | US9...)
Affinity DataIC50: 570nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetDiacylglycerol O-acyltransferase 1(Human)
Novartis

US Patent
LigandPNGBDBM161384(US9108956, 10 | US9108956, 9 | US9108956, 11 | US9...)
Affinity DataIC50: 1.20E+3nMpH: 7.5 T: 2°CAssay Description:The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent