BDBM161161 US9682976, 47::US9682976, 50

SMILES Cn1nnn(-c2cc(Nc3ncc(F)c(N[C@@H]4C[C@@H]5CCCN5C(C)(C)C4)n3)ccc2O[C@H]2CCOC2)c1=O

InChI Key InChIKey=LDUSGAYKQIOKIX-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 161161   

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161161(US9682976, 50 | US9682976, 47)
Affinity DataEC50: <100nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
Go to US Patent

TargetInterleukin-2(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM161161(US9682976, 50 | US9682976, 47)
Affinity DataEC50: <100nMAssay Description:Primary T cell stimulation and IL2 ELISA: Human primary T cells (100,000 cells per well) were pre-incubated with or without test compound in Yssel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/14/2018
Entry Details
Go to US Patent