BDBM161090 US9051240, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-dimethylacetamide::US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-dimethyl-acetamide

SMILES CCCCOc1cccc(CCNCC(=O)N(C)C)c1

InChI Key InChIKey=GRHBODILPPXVKN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 161090   

TargetAmine oxidase [flavin-containing] B(Rat)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161090(US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-d...)
Affinity DataIC50: 2.31E+5nMpH: 7.4Assay Description:The enzyme activity was assessed with a radioenzymatic assay using the substrate 14C-phenylethylamine (PEA) specific for MAO-B.The mitochondrial pell...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/18/2016
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161090(US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-d...)
Affinity DataIC50: 5.80E+3nMT: 2°CAssay Description:Test compound is dissolved in DMSO 500× the highest final concentration desired in the IC50 assay. 30 ml of deionized water is pre-warmed to 37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetCytochrome P450 2D6(Human)
Newron Pharmaceuticals

US Patent
LigandPNGBDBM161090(US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-d...)
Affinity DataIC50: 5.80E+3nMT: 2°CAssay Description:Test compound is dissolved in DMSO 500× the highest final concentration desired in the IC50 assay. 30 ml of deionized water is pre-warmed to 37...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/5/2017
Entry Details
Go to US Patent

TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Southampton

Curated by ChEMBL
LigandPNGBDBM161090(US9447029, 2-[2-(3-Butoxyphenyl)-ethylamino]-N,N-d...)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human ERG assessed as reduction in channel tail current by plate-based planar patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMed