BDBM160945 US9108903, 10

SMILES COc1cc(F)ccc1Oc1cc(cc(c1C(=O)Nc1ccc(cc1)C(O)=O)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=ZYORVEKORXNUEM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 160945   

TargetSodium channel protein type 10 subunit alpha(Rat)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM160945(US9108903, 10)
Affinity DataIC50: 37nMAssay Description:Patch clamp electrophysiology was used to assess the efficacy and selectivity of sodium channel blockers in dorsal root ganglion neurons. Rat neurons...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent