BDBM1609 4-(2-Carbethoxyethenyl)- 11-cyclopropyl-5,1 l-dihydro-6H-dipyrido[3,2-b:2 ,3 -e][ 1,4]diazepin-6-one::Nevirapin 4-substituted deriv. 6c::ethyl (2Z)-3-{2-cyclopropyl-10-oxo-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-7-yl}prop-2-enoate

SMILES CCOC(=O)\C=C/c1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12

InChI Key InChIKey=KERJMCSPJPMIQJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1609   

TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM1609(ethyl (2Z)-3-{2-cyclopropyl-10-oxo-2,4,9,15-tetraa...)
Affinity DataAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed