BDBM160883 BDBM289103::US10093655, Example 53::US11014909, Example 53::US9107923, 53

SMILES Cc1c(-c2ccc(Oc3ncccc3OC(F)F)cc2)n(C)c(=O)[nH]c1=O

InChI Key InChIKey=OMWKYRHUGPLHEF-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 160883   

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160883(US10093655, Example 53 | US11014909, Example 53 | ...)
Affinity DataKi:  6.91nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160883(US10093655, Example 53 | US11014909, Example 53 | ...)
Affinity DataKi:  109nMAssay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., Dif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160883(US10093655, Example 53 | US11014909, Example 53 | ...)
Affinity DataKi:  109nMpH: 7.4Assay Description:The affinity of the compounds described herein was determined by competition binding assays similar to those described in Ryman-Rasmussen et al., "Di...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent

TargetD(1A) dopamine receptor(Human)
Pfizer

US Patent
LigandPNGBDBM160883(US10093655, Example 53 | US11014909, Example 53 | ...)
Affinity DataKi:  109nMAssay Description:D1 binding assays were performed using over-expressing LTK human cell lines. To determine basic assay parameters, ligand concentrations were determin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2021
Entry Details
Go to US Patent