BDBM1608 11-Cyclopropyl-5,l l-dihydro-4-(2-phenylethenyl)-6H-dipyrido[3,2-b:2 ,3 -e][1,4]diazepin-6-one::2-cyclopropyl-7-[(E)-2-phenylethenyl]-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),4,6,11,13-hexaen-10-one::Nevirapin 4-substituted deriv. 6b

SMILES O=C1Nc2c(\C=C\c3ccccc3)ccnc2N(C2CC2)c2ncccc12

InChI Key InChIKey=PXIHWTCYZMFDOH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1608   

TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM1608(2-cyclopropyl-7-[(E)-2-phenylethenyl]-2,4,9,15-tet...)
Affinity DataAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed