BDBM160769 US10167313, Compound 36::US9045524, 36

SMILES CC(C)(C)OC(=O)C[C@H](NC(=O)OC(C)(C)C)\C=C\S(=O)(=O)c1ccccc1

InChI Key InChIKey=VUAFUTLGMQEWHT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 160769   

TargetCaspase-1(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160769(US9045524, 36 | US10167313, Compound 36)
Affinity DataIC50: 3.33E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

TargetCaspase-5(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160769(US9045524, 36 | US10167313, Compound 36)
Affinity DataIC50: 3.33E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

TargetCaspase-7(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160769(US9045524, 36 | US10167313, Compound 36)
Affinity DataIC50: 3.33E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

TargetCaspase-9(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160769(US9045524, 36 | US10167313, Compound 36)
Affinity DataIC50: 3.33E+3nMT: 2°CAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

TargetCaspase-3(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160769(US9045524, 36 | US10167313, Compound 36)
Affinity DataIC50: 2.00E+3nMAssay Description:To test the efficacy of caspase-3 inhibitors at the cellular level, the ability of selected compounds to inhibit the proteolytic cleavage of PARP (po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2016
Entry Details
Go to US Patent

TargetCaspase-3(Human)
Novagenesis Foundation

US Patent
LigandPNGBDBM160769(US9045524, 36 | US10167313, Compound 36)
Affinity DataIC50: 2.00E+3nMAssay Description:Selectivity of compound 55, compound 63, compound 48, compound 57, compound 88 toward caspase-1 (pro-inflammatory group), caspase-5 (group I), caspas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2019
Entry Details
Go to US Patent