BDBM160593 US9045468, 7(+)::US9045468, 7(-)

SMILES Oc1ccc(nn1)-c1ccc2c(CN3CCC2(C3)c2ccc(Cl)cc2)c1

InChI Key InChIKey=NQZVQAKLVZGMOR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 160593   

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160593(US9045468, 7(-) | US9045468, 7(+))
Affinity DataIC50: 62.5nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160593(US9045468, 7(-) | US9045468, 7(+))
Affinity DataIC50: 6.40nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160593(US9045468, 7(-) | US9045468, 7(+))
Affinity DataIC50: 148nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160593(US9045468, 7(-) | US9045468, 7(+))
Affinity DataIC50: 16.6nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160593(US9045468, 7(-) | US9045468, 7(+))
Affinity DataIC50: 674nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM160593(US9045468, 7(-) | US9045468, 7(+))
Affinity DataIC50: 103nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2015
Entry Details
Go to US Patent