BDBM160508 US10093663, Example 42::US9682968, Example-42

SMILES CCO[C@H]1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)[C@@H](C1)c1ccc(cc1)C(=O)OCC

InChI Key InChIKey=RNTPRBUILGSJRH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 160508   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM160508(US9682968, Example-42 | US10093663, Example 42)
Affinity DataIC50: 0.240nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 uM), recombinant human complement factor B (expressed in drosophila cells and purified us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
Go to US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM160508(US9682968, Example-42 | US10093663, Example 42)
Affinity DataIC50: 240nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent