BDBM160495 US10093663, Example 32-3::US9682968, Example-32-3

SMILES COC1CCN(Cc2c(OC)cc(C)c3[nH]ccc23)C(C1)c1ccc(CO)cc1

InChI Key InChIKey=ZOAIHWVLHCYDGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 160495   

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM160495(US9682968, Example-32-3 | US10093663, Example 32-3)
Affinity DataIC50: 0.340nMAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 uM), recombinant human complement factor B (expressed in drosophila cells and purified us...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2018
Entry Details
Go to US Patent

TargetComplement factor B(Human)
Novartis

US Patent
LigandPNGBDBM160495(US9682968, Example-32-3 | US10093663, Example 32-3)
Affinity DataIC50: 340nMpH: 7.4 T: 2°CAssay Description:CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/22/2019
Entry Details
Go to US Patent