BDBM16029 N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenylbutan-2-yl]-3-(N-methylmethanesulfonamido)-5-(2-methylpropanoyl)benzamide::isophthalamide deriv. 7j

SMILES CC(C)C(=O)c1cc(cc(c1)C(=O)N[C@@H](Cc1ccccc1)[C@H](O)CNC1CC1)N(C)S(C)(=O)=O

InChI Key InChIKey=NQPODBUQGCOYHO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 16029   

TargetBeta-secretase 1(Human)
Merck Research Laboratories

LigandPNGBDBM16029(N-[(2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-phenyl...)
Affinity DataIC50: 240nMpH: 4.5 T: 2°CAssay Description:The assay was performed using a 96-well format on a HPLC equipped with four 96-well plate holders. Test compounds were preincubated with enzymes for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed