BDBM159796 BDBM50434862::US9040518, 10

SMILES CCCC[C@]1(CC)CS(=O)(=O)c2cc(CCC(O)=O)c(OC)cc2[C@H](N1)c1ccccc1

InChI Key InChIKey=BXZSTNOKQQGVMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 159796   

TargetIleal sodium/bile acid cotransporter(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM159796(US9040518, 10 | BDBM50434862)
Affinity DataIC50: 17nMT: 2°CAssay Description:On the day of the uptake experiment, 10 mM HEPES was added to Hank's Balanced Salt Solution, and the pH was adjusted to 7.4 with TRIS (HBSSH). The as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2015
Entry Details
Go to US Patent

TargetIleal sodium/bile acid cotransporter(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM159796(US9040518, 10 | BDBM50434862)
Affinity DataIC50: 17nMAssay Description:Inhibition of human ASBT expressed in HEK293 cells assessed as inhibition of [3H]-taurocholate uptake after 90 mins by scintillation counting analysi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed