BDBM1597 1 l-Cyclopropyl-4-[[(2-chlorophenyl)oxy]methyl]-5,11-dihydro-6H-dipyrido[3,2-b:2 ,3 -e][ 1,4]diazepin-6-one::7-(2-chlorophenoxymethyl)-2-cyclopropyl-2,4,9,15-tetraazatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3,5,7,12,14-hexaen-10-one::Nevirapin 4-substituted deriv. 4t

SMILES Clc1ccccc1OCc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12

InChI Key InChIKey=BWGVLNTWNOZOPX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 1597   

TargetGag-Pol polyprotein [600-1027,R876K]/[600-1155](Human immunodeficiency virus type 1)
Boehringer Ingelheim Pharmaceuticals

LigandPNGBDBM1597(7-(2-chlorophenoxymethyl)-2-cyclopropyl-2,4,9,15-t...)
Affinity DataIC50: 3.05E+3nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2004
Entry Details Article
PubMed