BDBM15953 1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)methyl]-piperidine-4-carboxylic Acid Isopropyl Amide::1-{[(4-amino-5-cyano-6-ethoxypyridin-2-yl)carbamoyl]methyl}-N-(propan-2-yl)piperidine-4-carboxamide::Aminopyridine-Based Inhibitor 34

SMILES CCOc1nc(NC(=O)CN2CCC(CC2)C(=O)NC(C)C)cc(N)c1C#N

InChI Key InChIKey=AEHOYSAJZSVRLQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15953   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15953(1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)m...)
Affinity DataIC50: 87nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15953(1-[(4-Amino-5-cyano-6-ethoxypyridin-2ylcarbamoyl)m...)
Affinity DataIC50: 130nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/28/2007
Entry Details Article
PubMed