BDBM159400 US9034921, E016::US9340521, E010

SMILES COc1ccc(Cc2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c3OCCCc3c2Cl)cc1

InChI Key InChIKey=WYLIOZNHSFRBJY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 159400   

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM159400(US9034921, E016 | US9340521, E010)
Affinity DataIC50: 0.978nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5x104 cells/well in RP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2015
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM159400(US9034921, E016 | US9340521, E010)
Affinity DataIC50: 1.60nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT2 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 1(Human)
Green Cross

US Patent
LigandPNGBDBM159400(US9034921, E016 | US9340521, E010)
Affinity DataIC50: 16.9nMpH: 7.4 T: 2°CAssay Description:For sodium-dependent glucose transport assay, cells expressing hSGLT1 were seeded into a 96-well culture plate at a density of 5×104 cells/well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2017
Entry Details
Go to US Patent

TargetSodium/glucose cotransporter 2(Human)
Green Cross

US Patent
LigandPNGBDBM159400(US9034921, E016 | US9340521, E010)
Affinity DataIC50: 0.980nMAssay Description:Inhibition of human SGLT2 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed
TargetSodium/glucose cotransporter 1(Human)
Green Cross

US Patent
LigandPNGBDBM159400(US9034921, E016 | US9340521, E010)
Affinity DataIC50: 17nMAssay Description:Inhibition of human SGLT1 expressed in CHO cells by methyl-alpha-D-glucopyranoside assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed