BDBM159345 US9034899, 36::US9173879, 1 (-) - enantiomer::US9604960, 36

SMILES Clc1ccc(cc1Cl)C1CNCc2cc(ccc12)-c1ccc2ncnn2c1

InChI Key InChIKey=VXVOMCCQHIVMJK-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 159345   

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 30.8nMpH: 7.9 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 4.20nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 30.8nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 105nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 4.80nMpH: 7.5 T: 2°CAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2016
Entry Details
Go to US Patent

TargetSodium-dependent serotonin transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 1.80nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSodium-dependent dopamine transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 31nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Albany Molecular Research

US Patent
LigandPNGBDBM159345(US9034899, 36 | US9173879, 1 (-) - enantiomer | US...)
Affinity DataIC50: 26nMAssay Description:Compounds were dissolved in 100% DMSO at a concentration 100 times the desired highest assay concentration, serially diluted 1:3 in 100% DMSO, and 1....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
Go to US Patent