BDBM15918 2-pyridinecarboxamide deriv. 12::4-Amino-5-chloro-6-ethoxy-pyridine-2-carboxylic acid 4-methanesulfonyl-benzylamide::4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphenyl)methyl]pyridine-2-carboxamide::CHEMBL377383

SMILES CCOc1nc(cc(N)c1Cl)C(=O)NCc1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=ZVDDPXIWKBBCQE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 15918   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15918(4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphe...)
Affinity DataIC50: 24nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15918(4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphe...)
Affinity DataIC50: 74nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15918(4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphe...)
Affinity DataIC50: 74nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15918(4-amino-5-chloro-6-ethoxy-N-[(4-methanesulfonylphe...)
Affinity DataIC50: 24nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed