BDBM15915 2-pyridinecarboxamide deriv. 8e::4-Amino-5-cyano-6-ethoxy-pyridine-2-carboxylic acid (pyridin-3-ylmethyl)-amide::4-amino-5-cyano-6-ethoxy-N-(pyridin-3-ylmethyl)pyridine-2-carboxamide

SMILES CCOc1nc(cc(N)c1C#N)C(=O)NCc1cccnc1

InChI Key InChIKey=SZBUKBINUVLFEL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15915   

TargetMitogen-activated protein kinase 8(Human)
Abbott Laboratories

LigandPNGBDBM15915(4-amino-5-cyano-6-ethoxy-N-(pyridin-3-ylmethyl)pyr...)
Affinity DataIC50: 26nMpH: 7.2 T: 2°CAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Abbott Laboratories

LigandPNGBDBM15915(4-amino-5-cyano-6-ethoxy-N-(pyridin-3-ylmethyl)pyr...)
Affinity DataIC50: 41nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/24/2007
Entry Details Article
PubMed