BDBM158662 US9034866, 137

SMILES CNC(=O)c1c(nc2-c3cc(C#C[C@@](C)(O)c4cc(C)on4)c(F)cc3C3CC(C3)n12)C(N)=O

InChI Key InChIKey=GFVXWRXUSFUWQS-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 158662   

LigandPNGBDBM158662(US9034866, 137)
Affinity DataKi:  8nMpH: 7.2Assay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5'-triphosphate (ATP) was monitored u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2015
Entry Details
Go to US Patent

LigandPNGBDBM158662(US9034866, 137)
Affinity DataKi:  14nMAssay Description:Inhibition of NIK (unknown origin) using ATP as substrate by transcreener ADP assay based fluorescence correlation spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2021
Entry Details Article
PubMed