BDBM158487 US10383835, Compound 2226::US9029401, 2253

SMILES CNC(=O)c1ccc(O[C@H]2CCC(CC2)NC(=O)Nc2ccc(Cl)c(c2)C(F)(F)F)cc1

InChI Key InChIKey=XMHPFTJYRYODSK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 158487   

TargetBifunctional epoxide hydrolase 2(Human)
University of California

US Patent
LigandPNGBDBM158487(US9029401, 2253 | US10383835, Compound 2226)
Affinity DataIC50: 0.5nMAssay Description:See reference (Jones, P. D.; Wolf, N. M.; Morisseau, C.; Whetstone, P.; Hock, B.; Hammock, B. D. Anal. Biochem. 343:66-75; 2005) for sEH assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
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TargetEpoxide hydrolase(Horse)
University of California

US Patent
LigandPNGBDBM158487(US9029401, 2253 | US10383835, Compound 2226)
Affinity DataIC50: 1nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
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TargetEpoxide hydrolase(Sheep)
University of California

US Patent
LigandPNGBDBM158487(US9029401, 2253 | US10383835, Compound 2226)
Affinity DataIC50: 1nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent

TargetEpoxide hydrolase 1(Cat)
University of California

US Patent
LigandPNGBDBM158487(US9029401, 2253 | US10383835, Compound 2226)
Affinity DataIC50: 4nMAssay Description:The enzyme also can be detected based on the binding of specific ligands to the catalytic site which either immobilize the enzyme or label it with a ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent