BDBM158460 US9029399, 32A-II::US9339501, 32A-II

SMILES FC(F)(F)c1cc(ccn1)N1[C@H]2C[C@H]2N(C1=O)c1cnccc1C1CC1

InChI Key InChIKey=HHSNJLVYXKJDIO-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 158460   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Novartis

US Patent
LigandPNGBDBM158460(US9029399, 32A-II | US9339501, 32A-II)
Affinity DataIC50: 6.90nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
Go to US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Novartis

US Patent
LigandPNGBDBM158460(US9029399, 32A-II | US9339501, 32A-II)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2015
Entry Details
Go to US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Novartis

US Patent
LigandPNGBDBM158460(US9029399, 32A-II | US9339501, 32A-II)
Affinity DataIC50: 6.90nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
Go to US Patent

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Novartis

US Patent
LigandPNGBDBM158460(US9029399, 32A-II | US9339501, 32A-II)
Affinity DataIC50: 3nMpH: 7.5Assay Description:Assay method was adopted from a published protocol with some modifications to suit our requirements (Dmitry N Grigoryev et al, Analytical Biochemistr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/31/2017
Entry Details
Go to US Patent