BDBM15831 1-[(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]methyl}-1H-indol-2-yl)carbonyl]-N-(propan-2-yl)piperidin-4-amine::2-carboxyindole-based inhibitor 16

SMILES CC(C)NC1CCN(CC1)C(=O)c1cc2ccccc2n1Cc1cc(on1)-c1ccc(Cl)s1

InChI Key InChIKey=HAHDTUXAQNSETN-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15831   

TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM15831(1-[(1-{[5-(5-chlorothiophen-2-yl)-1,2-oxazol-3-yl]...)
Affinity DataKi:  3.00E+3nM ΔG°:  -7.53kcal/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2007
Entry Details Article
PubMed