BDBM156487 US9023354, AD4-13062

SMILES Oc1c(ccc2cccnc12)C(Nc1ccc(nc1)C(F)(F)F)c1cc(ccc1Cl)C(F)(F)F

InChI Key InChIKey=MHXDFMCFQCOGME-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 156487   

TargetE3 ubiquitin-protein ligase Mdm2(Human)
TBA

US Patent
LigandPNGBDBM156487(US9023354, AD4-13062)
Affinity DataIC50: 4.40E+4nMT: 2°CAssay Description:The following example describes an assay that measured the ability of compounds to inhibit the binding of p53 to MDM2 using the AlphaScreen assay tec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
US Patent