BDBM156327 US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine::US9592230, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H-imidazol-2-yl)-ethyl]-[1,2,4]triazolo[1,5-a]pyrimidine

SMILES Cc1cc(C)n2nc(CCc3nc(cn3C)-c3ccccc3)nc2n1

InChI Key InChIKey=CHOZGBJYIPUZGG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 156327   

LigandPNGBDBM156327(US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H...)
Affinity DataIC50: 12nMT: 2°CAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/11/2015
Entry Details
Go to US Patent

LigandPNGBDBM156327(US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H...)
Affinity DataIC50: 12nMAssay Description:A PDE10A assay may for example, be performed as follows: The assay is performed in 60 uL samples containing a fixed amount of the relevant PDE enzyme...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
Go to US Patent

LigandPNGBDBM156327(US9018217, 5,7-Dimethyl-2-[2-(1-methyl-4-phenyl-1H...)
Affinity DataIC50: 67nMAssay Description:Inhibition of PDE10 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed