BDBM15615 4-(4-(3-Chlorophenyl)-1H-pyrazol-3-yl)-N-ethyl-N-methyl-1H-pyrrole-2-carboxamide::4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-ethyl-N-methyl-1H-pyrrole-2-carboxamide::Pyrrole Carboxamide Analog 5a

SMILES CCN(C)C(=O)c1cc(c[nH]1)-c1n[nH]cc1-c1cccc(Cl)c1

InChI Key InChIKey=SVGGWCSPGCMEAQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15615   

TargetMitogen-activated protein kinase 1(Human)
Vertex Pharmaceuticals

LigandPNGBDBM15615(4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-ethyl-N-m...)
Affinity DataKi:  580nM ΔG°:  -8.64kcal/molepH: 7.5 T: 2°CAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Vertex Pharmaceuticals

LigandPNGBDBM15615(4-[4-(3-chlorophenyl)-1H-pyrazol-3-yl]-N-ethyl-N-m...)
Affinity DataKi: >4.00E+3nMAssay Description:A coupled spectrophotometric assay was used in which ADP generated by ERK2 was converted to ATP by pyruvate kinase with the production of pyruvate fr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/14/2007
Entry Details Article
PubMed