BDBM155556 US9012461, 32

SMILES NC(=O)Cc1cccnc1CCc1nc(Nc2ccc(cc2)C2CCNCC2)ncc1C(F)(F)F

InChI Key InChIKey=QQQMWFVEOMAALF-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155556   

TargetFocal adhesion kinase 1(Human)
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155556(US9012461, 32)
Affinity DataIC50: 3.5nMpH: 7.4Assay Description:A biotin labeled peptide is used as substrate (amino acid sequence: Biotin-Glu-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Met-Asp-Phe-NH2)1S...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetFocal adhesion kinase 1(Human)
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155556(US9012461, 32)
Affinity DataKd:  2.5nMpH: 7.4 T: 2°CAssay Description:Binding parameters of compounds were determined using a Biacore S51 sensor. An anti-GST antibody was immobilized onto a CM5 chip by primary amine-cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent

TargetFocal adhesion kinase 1(Human)
Cancer Therapeutics Crc

US Patent
LigandPNGBDBM155556(US9012461, 32)
Affinity DataIC50: 5.10nMpH: 7.0Assay Description:Compounds of the invention may be tested for in vitro activity in the following assay: A biotin labeled peptide is used as substrate (amino acid sequ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2015
Entry Details
Go to US Patent