BDBM15547 (3R,6S)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-ethyl-6-methyl-1,4-diazepan-2-one::6-methyl diazepanone 14c

SMILES CC[C@H]1N(C[C@@H](C)CNC1=O)C(=O)C[C@H](N)Cc1cc(F)c(F)cc1F

InChI Key InChIKey=GTZPAVVEMVRYBF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 15547   

TargetDipeptidyl peptidase 4(Human)
Merck Research Laboratories

LigandPNGBDBM15547((3R,6S)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50: 37.3nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 2(Human)
Merck Research Laboratories

LigandPNGBDBM15547((3R,6S)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50: 6.10E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Merck Research Laboratories

LigandPNGBDBM15547((3R,6S)-4-[(3R)-3-amino-4-(2,4,5-trifluorophenyl)b...)
Affinity DataIC50: 4.10E+4nMAssay Description:The enzyme activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 360 nm and m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/11/2007
Entry Details Article
PubMed