BDBM155462 US9006454, I104

SMILES Cc1cc(C(O)=O)c2[nH]c(nc2c1)-c1c(F)c(F)c(-c2cccc(O)c2)c(F)c1F

InChI Key InChIKey=SEBXJVNLSSBOPQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 155462   

LigandPNGBDBM155462(US9006454, I104)
Affinity DataIC50: 13.5nMpH: 8.0Assay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
US Patent