BDBM155397 US9006454, I1

SMILES OC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PQUMFZORRCNBES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 155397   

LigandPNGBDBM155397(US9006454, I1)
Affinity DataIC50: 795nMpH: 8.0Assay Description:The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
Go to US Patent

LigandPNGBDBM155397(US9006454, I1)
Affinity DataIC50: 750nMAssay Description:Inhibition of human DHODH using L-DHO, DUQ, DCIP as substrate preincubated for 30 mins followed by substrate addition measured after 2 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2016
Entry Details Article
PubMed