BDBM155369 US10383871, Example 19::US10918640, Example 19::US9006269, 19

SMILES COc1cccc(c1F)-c1ccc(OC2CN(C2)C(=O)Nc2cccnn2)nc1

InChI Key InChIKey=GQVNLDQKGBHOIC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 155369   

TargetFatty-acid amide hydrolase 1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM155369(US9006269, 19 | US10383871, Example 19 | US1091864...)
Affinity DataIC50: 26nMpH: 8.2 T: 2°CAssay Description:Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/26/2015
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM155369(US9006269, 19 | US10383871, Example 19 | US1091864...)
Affinity DataIC50: 26nMAssay Description:Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/13/2020
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Vernalis (R&D)

US Patent
LigandPNGBDBM155369(US9006269, 19 | US10383871, Example 19 | US1091864...)
Affinity DataIC50: 26nMAssay Description:Human FAAH 1 activity was determined by measuring the liberation of the highly fluorescent 7-amino, 4-methyl Coumarin (AMC) generated during hydrolys...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent