BDBM15513 (4R,5R)-5-Amino-1-(4-(methylsulfonyl)phenethyl)-4-(2,4,5-trifluorophenyl)piperidin-2-one::(4R,5R)-5-amino-1-[2-(4-methanesulfonylphenyl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one::Piperidinone-Constrained Phenethylamine 33

SMILES CS(=O)(=O)c1ccc(CCN2C[C@H](N)[C@H](CC2=O)c2cc(F)c(F)cc2F)cc1

InChI Key InChIKey=JCQUUJJIHVDGMV-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15513   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15513((4R,5R)-5-amino-1-[2-(4-methanesulfonylphenyl)ethy...)
Affinity DataKi:  12nM ΔG°:  -10.7kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed