BDBM15512 (4S,5S)-5-amino-1-(2-(benzo[d][1,3]dioxol-5-yl)ethyl)-4-(2,4,5-trifluorophenyl)piperidin-2-one::(4S,5S)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethyl]-4-(2,4,5-trifluorophenyl)piperidin-2-one::Piperidinone-Constrained Phenethylamine 32

SMILES N[C@@H]1CN(CCc2ccc3OCOc3c2)C(=O)C[C@H]1c1cc(F)c(F)cc1F

InChI Key InChIKey=DIRIFWIKLRTNMB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15512   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15512((4S,5S)-5-amino-1-[2-(2H-1,3-benzodioxol-5-yl)ethy...)
Affinity DataKi:  105nM ΔG°:  -9.42kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed