BDBM15505 (4R,5R)-5-amino-1-(2-phenylethyl)-4-(2,4,5-trifluorophenyl)piperidin-2-one::4, 5-trans -5-Amino-1-phenethyl-4-(2,4,5-trifluorophenyl)piperidin-2-one::Piperidinone-Constrained Phenethylamine 20::Racemic mixture

SMILES N[C@H]1CN(CCc2ccccc2)C(=O)C[C@@H]1c1cc(F)c(F)cc1F

InChI Key InChIKey=JSLGFCYDVSMEIL-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 15505   

TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15505((4R,5R)-5-amino-1-(2-phenylethyl)-4-(2,4,5-trifluo...)
Affinity DataKi:  17nM ΔG°:  -10.5kcal/molepH: 7.5 T: 2°CAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2007
Entry Details Article
PubMed