BDBM154578 Carmaphycin A (1)

SMILES CCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCS(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1

InChI Key InChIKey=KLYPRXGLYCCNGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 154578   

TargetProteasome subunit alpha type-2(Baker's yeast)
University of California San Diego

LigandPNGBDBM154578(Carmaphycin A (1))
Affinity DataIC50: 1.5nMpH: 7.5Assay Description:One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetProteasome subunit alpha type-2(Baker's yeast)
University of California San Diego

LigandPNGBDBM154578(Carmaphycin A (1))
Affinity DataIC50: 46.2nMpH: 7.5Assay Description:One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed