BDBM154545 3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UNC2170, 1)

SMILES CC(C)(C)NCCCNC(=O)c1cccc(c1)Br

InChI Key InChIKey=XUFUVCIZFNREBI-UHFFFAOYSA-N

Data  10 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 154545   

TargetTP53-binding protein 1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 2.90E+4nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetChromobox protein homolog 7(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPHD finger protein 1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPHD finger protein 19(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetPHD finger protein 23(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase UHRF1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetMBT domain-containing protein 1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:In brief, compound plates (1 μL at 10 mM highest concentration; 3-fold, 10-point dilutions in DMSO) were diluted in 1X assay buffer (20 mM TRIS ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataKd:  2.20E+4nMpH: 8.0 T: 2°CAssay Description:All ITC measurements were recorded at 25 °C with an AutoITC200 microcalorimeter (MicroCal Inc.). All protein and compound stock samples were in the t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTP53-binding protein 1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataKd:  2.20E+4nMAssay Description:Binding affinity to 53BP1 methyllysine binding domain (unknown origin) by ITC methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTP53-binding protein 1(Human)
University of North Carolina at Chapel Hill

LigandPNGBDBM154545(3-Bromo-N-(3-(tert-butylamino)propyl)benzamide (UN...)
Affinity DataIC50: 3.00E+4nMAssay Description:Competitive displacement of p53K382me2 from His-tagged 53BP1 tandem Tudor domain (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)