BDBM154323 US9012443, 343

SMILES COc1cc(-c2cc(F)cc(F)c2)c(cc1-c1nccc2cc(ccc12)S(=O)(=O)Nc1ccon1)C#N

InChI Key InChIKey=WVTZRURPOGWBCC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 154323   

LigandPNGBDBM154323(US9012443, 343)
Affinity DataIC50: 145nMAssay Description:293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154323(US9012443, 343)
Affinity DataIC50: 3.00E+4nMAssay Description:293 cells stably transfected with Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology system acco...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2015
Entry Details
Go to US Patent

LigandPNGBDBM154323(US9012443, 343)
Affinity DataIC50: 140nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells incubated for 3 to 5 mins at -125 mV holding potential by electrophysiology assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2019
Entry Details Article
PubMed