BDBM153638 US8999980, I-60

SMILES CC1=C[C@](C)(N=C(N)O1)c1cc(NC(=O)c2ncc(cc2F)C#N)ccc1F

InChI Key InChIKey=QIGLYAWWYQUXSG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153638   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM153638(US8999980, I-60)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent