BDBM153627 US8999980, I-4

SMILES C[C@]1(CC(=C)OC(N)=N1)c1cc(NC(=O)c2ncc(Cl)cc2Cl)ccc1F

InChI Key InChIKey=GENVKVISQDWGTR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153627   

TargetBeta-secretase 1(Human)
Shionogi

US Patent
LigandPNGBDBM153627(US8999980, I-4)
Affinity DataIC50: 3.00E+4nMpH: 5.0 T: 2°CAssay Description:48.5 .mu.L of substrate peptide solution (Biotin-XSEVNLDAEFRHDSGC-Eu: X=.epsilon.-amino-n-capronic acid, Eu=Europium cryptate) was added to each well...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details
Go to US Patent