BDBM153410 4-(Cyclopentylamino)-8-methyl-6-(3-(oxazol-2-yl)phenyl)quinoline-3-carboxamide (28)

SMILES Cc1cc(cc2c(NC3CCCC3)c(cnc12)C(N)=O)-c1cccc(c1)-c1ncco1

InChI Key InChIKey=LWQVMGPQORZRKF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 153410   

TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

LigandPNGBDBM153410(4-(Cyclopentylamino)-8-methyl-6-(3-(oxazol-2-yl)ph...)
Affinity DataIC50: 5.90E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25µM cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed