BDBM153394 Methyl 3-(3-carbamoyl-4-((3-methoxyphenyl)amino)-8-methylquinolin-6-yl)benzoate (17a)

SMILES COC(=O)c1cccc(c1)-c1cc(C)c2ncc(C(N)=O)c(Nc3cccc(OC)c3)c2c1

InChI Key InChIKey=JYPQYRGDTUHVIB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 153394   

TargetPhosphodiesterase(Trypanosoma brucei)
Northeastern University

LigandPNGBDBM153394(Methyl 3-(3-carbamoyl-4-((3-methoxyphenyl)amino)-8...)
Affinity DataIC50: 6.40E+3nMpH: 7.4Assay Description:In short, recombinant TbrPDEB1 and TbrPDEB2 were assayed in 10 mM Tris pH 7.4, bovine serum albumin (0.2 mg/mL), 10 mM MgCl2, 25µM cAMP (Enzo Lifesci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Northeastern University

LigandPNGBDBM153394(Methyl 3-(3-carbamoyl-4-((3-methoxyphenyl)amino)-8...)
Affinity DataIC50: 4.20E+4nMAssay Description:This assay was performed at Takeda Pharmaceuticals using methods previously reported.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2015
Entry Details Article
PubMed