BDBM15333 3-[2-chloro-4-({2-[(3-nitrophenyl)methyl]-3-oxocyclohex-1-en-1-yl}amino)phenyl]-4,4-dimethyl-4,5-dihydro-1H-pyrazol-5-one::Aryldimethylpyrazolone 18l

SMILES CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3cccc(c3)[N+]([O-])=O)C(=O)CCC2)cc1Cl

InChI Key InChIKey=JWTQCBIRFQQGLI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 15333   

TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3B [387-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15333(3-[2-chloro-4-({2-[(3-nitrophenyl)methyl]-3-oxocyc...)
Affinity DataIC50: 30nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A [388-1112](Human)
Merck Research Laboratories

LigandPNGBDBM15333(3-[2-chloro-4-({2-[(3-nitrophenyl)methyl]-3-oxocyc...)
Affinity DataIC50: 550nMAssay Description:PDE activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using scintillation proximity assay (SPA). [3H]-AMP was captured by t...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/7/2007
Entry Details Article
PubMed