BDBM153270 3,5,7-trihydroxy-2-(2-hydroxyphenyl)chromen-4-one::Datiscetin (16)::Datiscetin (Dat)

SMILES c1ccc(c(c1)C2=C(C(=O)c3c(cc(cc3O2)O)O)O)O

InChI Key InChIKey=WCNLFPKXBGWWDS-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 153270   

TargetAurora kinase B(Human)
Konkuk University

LigandPNGBDBM153270(3,5,7-trihydroxy-2-(2-hydroxyphenyl)chromen-4-one ...)
Affinity DataIC50: 1.78E+4nMAssay Description:The kinase assay was performed using the EMD Millipore KinaseProfiler service assay protocol. Aurora B kinase was supplied by EMD Millipore Corp. The...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/1/2015
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

LigandPNGBDBM153270(3,5,7-trihydroxy-2-(2-hydroxyphenyl)chromen-4-one ...)
Affinity DataIC50: 5.54E+4nMpH: 7.4 T: 2°CAssay Description:Fluorescence intensity was measured at 420 nm excitation and 485 nm emission using a microplate reader (MPR-A4 II; TOSOH, Tokyo, Japan, or Fluoroskan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2017
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

LigandPNGBDBM153270(3,5,7-trihydroxy-2-(2-hydroxyphenyl)chromen-4-one ...)
Affinity DataIC50: 5.54E+4nMAssay Description:Inhibition of wild type Amyloid beta (1 to 42) (unknown origin) aggregation by Thioflavin-T fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2017
Entry Details Article
PubMed